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Frequency of Dyslipidaemia in Ischemic Stroke Patients at Tertiary Care Hospital

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Abstract

This study aimed to determine the frequency of dyslipidaemia among ischemic stroke patients presenting to tertiary care Khyber Teaching Hospital, Peshawar. A cross-sectional study was conducted from 15 October 2022 to 14 April 2023, including 203 ischemic stroke patients. Dyslipidaemia was assessed using fasting lipid profiles and defined based on NCEP ATP III criteria. Data were analysed using SPSS version 25.0, and associations were evaluated with chi-square tests. A p-value of < 0.05 was considered statistically significant. Among 203 patients, 67.0% had dyslipidaemia. Elevated LDL levels were observed in 48.7%, elevated triglycerides in 58.1%, and elevated total cholesterol in 45.3%, while low HDL was noted in 62.4% of patients. Dyslipidaemia prevalence was higher in males (p = 0.023), with 74.5% of dyslipidaemia patients being overweight or obese (p = 0.008). Comorbid conditions, including hypertension (81.6%) and diabetes mellitus (52.2%), were significantly associated with dyslipidaemia (p = 0.016 and p = 0.024, respectively). Dyslipidaemia is highly prevalent among ischemic stroke patients, with significant associations with gender, BMI, and comorbid conditions. These findings underscore the need for early identification and management of dyslipidaemia to prevent stroke and improve outcomes in rural populations.

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  • Atherosclerosis
  • Carotid artery disease
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  • Dyslipidaemias
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  • Stroke

Data Availability

No datasets were generated or analysed during the current study.

Code Availability

Not applicable.

References

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Funding

This study did not receive any funding.

Author information

Authors and Affiliations

  1. Department of Medicine, Khyber Teaching Hospital, Peshawar, Pakistan

    Zeeshan Ahmad, Bughdad Khan Wazir, Muhammad Imran & Kamran Saeed

  2. Department of Medicine, Hayatabad Medical Complex, Peshawar, Pakistan

    Asif Khan

  3. Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan

    Syed Murtaza Shah Bukhari, Sajjad Mohammad, Muhmmad Irfan Shereen & Saif ul Islam

  4. Deparment of Radiology, Iqra National University, Peshawar, Pakistan

    Mian Zia Shah

Contributions

B.K.W. and A.K. conceived and designed the study. Z.A. and M.I. contributed to data collection and analysis. S.M.S.B. and M.Z.S. performed the statistical analysis and interpreted the data. S.M., M.I.F., and S.U.I. provided critical input during manuscript revision, including review of the methodology, discussion, and reference updates. K.S. supervised the study and revised the manuscript. All authors contributed to the writing and critical review of the manuscript. B.K.W. and K.S. finalized the manuscript for submission.

Corresponding author

Correspondence to Kamran Saeed.

Ethics declarations

Ethics Approval

This retrospective study was conducted in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Ethical approval was obtained from the Institutional Review and Ethical Board (IREB) of Khyber Medical College, Peshawar (Reference No. 399/DME/KMC).

Consent to Participate

For this retrospective study, formal consent was not required, as all patient data were anonymized and maintained with strict confidentiality in accordance with institutional guidelines.

Consent for Publication

Not applicable.

Conflict of interest

The authors declare no competing interests.

Additional information

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Cite this article

Ahmad, Z., Wazir, B.K., Khan, A. et al. Frequency of Dyslipidaemia in Ischemic Stroke Patients at Tertiary Care Hospital. SN Compr. Clin. Med. 7, 212 (2025). https://doi.org/10.1007/s42399-025-01972-7

  • Received
  • Revised
  • Accepted
  • Published
  • DOI https://doi.org/10.1007/s42399-025-01972-7

Keywords

  • Dyslipidaemia
  • Ischemic stroke
  • Lipid abnormalities
  • Rural health
  • Pakistan

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